Job Description

Associate Scientist (Tarrytown, NY)

Regeneron Pharmaceuticals, Inc. seeks an Associate Scientist (Tarrytown, NY) to conduct laboratory experiments supporting the design, development, and functional validation of gene therapy platforms, gene editing technologies, novel viral vectors, and nucleic acid therapeutics targeting neurological and neurodegenerative diseases. Support technology development for antibody-based strategies to improve targeted drug delivery across the blood brain barrier (BBB), to the CNS and into specific tissues and cell types of interest. Plan and perform experiments to functionally validate novel targeted drugs (siRNAs, ASOs, shRNAs, CRISPR systems, vectorized antibodies or peptides) and viral vectors in in vitro models. Perform cell culture with immortalized cell lines, iPSC-derived cells and primary cultures, and cell-based assays (ICC, flow cytometry). Plan, initiate, and complete molecular biology and biochemistry assays: molecular cloning, PCR, RT-qPCR, RNA sequencing, ELISAs, IP, WB, CE-western. Perform advanced data analysis (Halo, ImageJ, FlowJo, Prism) and troubleshooting under minimal supervision. Keep up-to-date and well-organized records of experimental protocols and results. Communicate and report experimental findings at group and departmental meetings. Survey current and relevant literature to expand scientific and technical knowledge and optimize and develop new assays.

SALARY RANGE: $74,838.00 - $110,100.00 per year

Job Requirements:

Requires a Bachelor’s degree in Biology, Neuroscience, Clinical Research, or a related field, and 1 year of in vitro lab experience. Must have experience with: Neuroscience, molecular tools for CNS targeting, in vitro models of neurodegenerative disorders; Aseptic technique and culturing various in vitro cell lines such as HEK293T and primary neurons; Working with iPSC-derived cells with knowledge in differentiation protocols to generate iPSC-derived neurons and other CNS cell types; Generating lentivirus and leveraging them to generate stable cell lines in vitro; Cell-based assay techniques, including immunocytochemistry/immunofluorescence (ICC/IF) and flow cytometry; Molecular biology techniques and biochemical assays, including cloning, sequencing, PCR, RT-qPCR, ELISA, immunoprecipitation, and western blot; and Data analysis using ImageJ, Prism, and sequence alignment tools.

Apply at Reference code: R46271.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

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